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  Duloxetine is novel selective serotonin (5-HT) and norepinephrine (NE) dual reuptake inhibitor (SNRI). The chemical name is N-methyl-(1-naphthol) -2-chlorphenamine hydrochloride. The study found that duloxetine not only can treat depression but also has good prospects for chronic pain with fewer side effects and no weight gain or sexual dysfunction. And significantly improve insomnia, tardiness, pain, and headaches, which are usually not achieved with serotonin reuptake inhibitors. Duloxetine was approved by the U.S. Food and Drug Administration (FDA) in 2002 as an antidepressant to be marketed in the U.S. In August 2006,  duloxetine  was approved in China. It has become an important weapon for pain and rheumatologists due to its excellent efficacy in the treatment of chronic pain. In September 2004, duloxetine received a new indication in the United States for the treatment of adult diabetic painful peripheral neuropathy, becoming the first drug to be officially approv...

  Fumaric acid The chemical name of fumaric acid is fumaric acid. It is a carboxylic acid derived from butene. It was first discovered from fumaric acid, also known as fumaric acid. Fumaric acid is the simplest unsaturated dicarboxylic acid, so it is an important chemical raw material. The annual production of  fumaric acid  in my country is more than 1 million tons, and it is widely used in medicine, food, and other fields. The research on fumaric acid in the field of medicine is more thorough, and its derivatives are often used to treat diseases such as psoriasis, arthritis, and cerebrospinal sclerosis. In the food field, they are mostly used as raw materials for the production of nutritional fortifiers and acidity regulators. GB2760 stipulates that fumaric acid and monosodium fumarate can be used in gum-based candies, wet noodle products, barbecued food, and other categories. The application range of fumaric acid and monosodium fumarate in food is different, mainly due...